Disinfection Efficacy Testing (DET)

We deliver a complete range of testing services to validate your disinfection protocols thoroughly. Our comprehensive testing approach combines standard USP methodologies with customized protocols designed specifically for your facility's needs, including testing against the USP standard organisms and contaminants isolated from your facility, providing you with robust validation data for all critical control points.

Core testing capabilities:

• Disinfectant efficacy testing for bacteria and mold (vegetative and spore-forming)
• Efficacy testing for antiviral activity
• Custom kill-time studies
• Recovery studies on facility surfaces
• Neutralization validation
• Suspension preparation for facility isolates

Range of services offered:

• Guidance on DET study design
• Customized study design
• Custom methods – wet contact, wipe, mop
• Development of robust disinfectant protocol
• Recovery studies on custom surfaces
• Neutralization of disinfectant
• Efficacy studies – surface disinfectant organism vs. contact time
• Customized suspension preparation for in-house isolates – recovered from facility
• Kill time studies – dilution
• Customized reporting

Your facility's success depends on effective disinfection across all critical surfaces. We provide comprehensive testing for every surface type in your controlled environment, from standard cleanroom materials to custom components. Our validation protocols cover the full spectrum of materials present in your facility, giving you complete confidence in your disinfection strategy.

Surface types we validate:

• Standard cleanroom surfaces
• Custom facility materials
• Production equipment surfaces
• Storage area materials
• Transfer system components

Your disinfection protocols deserve validation that matches your real-world application methods. Our lab will test your chosen disinfectants using your disinfectant application methods, adapting our testing approach to mirror your facility's specific procedures, from contact times to application techniques. This ensures your validation data accurately reflects your operational practices and meets regulatory requirements.

Disinfectant Efficacy Testing for Bacteria and Mold (Vegetative & Spore-Forming)
Surfaces commonly found in GMP manufacturing facilities are inoculated with test bacteria and mold, including routine contaminants identified during production. These surfaces are then disinfected using the facility’s standard procedures. After treatment, surviving organisms are measured to determine the disinfectant’s effectiveness. The GMP facility sets the required reduction level for qualification testing.

Disinfectant Efficacy Testing for Antiviral Activity
GMP facility surfaces are inoculated with test viruses and any routine viral contaminants identified during manufacturing. The surfaces are then disinfected using the facility’s usual methods. After treatment, virus survival is assessed using a virus-specific assay. The GMP facility determines the necessary reduction level for effective disinfection.

We understand that disinfectant studies can be a bottleneck in getting your facility up and running with confidence. Our team works alongside you to develop comprehensive testing protocols that address your specific needs. With analysts devoted to disinfectant studies, we provide regular communication throughout the testing process, including notifications of any test failures. This collaborative approach results in robust disinfection strategies backed by thorough validation data that supports your contamination control program.

Our team operates from Life Sciences hubs across the world, providing global access to our expert capabilities. Find your nearest Life Sciences hub on our Locations Page.